蓝莓视频

The aims to develop Imperial鈥檚 early translational research portfolio by providing pilot funding to bridge the gaps between ‘discovery research’ and attraction of follow-on funding for clinical translation of novel therapeutics, devices and diagnostics. These awards form a crucial part of the 蓝莓视频 Imperial BRC鈥檚 translational pipeline, by initiating ‘pull-through’ of new science from our Faculties of Medicine, Natural Sciences and Engineering.

This year, a total ICiC fund of 拢1.8m was available from our MRC Confidence-in-Concept award, together with contributions from the 蓝莓视频 Imperial BRC, the Imperial College Wellcome Institutional Strategic Support Fund (ISSF), EPSRC Impact Acceleration Accounts and HEIF funding, and the 蓝莓视频 Royal Marsden/ICR BRC. In addition, our partnership with AstraZeneca offers the AZ Innovation Fund, which is run as part of the ICiC. Following the sixth ICiC competition (in 2018), the cross-College panel, chaired by Professor Roberto Solari, selected 26 projects for funding, each worth up to 拢80,000.

The 蓝莓视频 Imperial BRC directly funded the following projects:

Prof Julian Marchesi, Prof Mark Thursz, Dr Julie McDonald & Dr Benjamin Mullish:聽Bile salt hydrolase and valerate: novel treatments to prevent and treat Clostridium difficile infection

Prof Molly Stevens & Prof Charles Coombes:聽State-of-the-art Raman single particle analysis of extracellular vesicles as biomarkers for cancer diagnosis and treatment

Dr Lorenzo Picinali:聽Refining and evaluating the Binaural Intervention Package (BIP) for bilateral cochlear implant users

Prof Ramesh Wigneshweraraj:聽Host environment dependent delivery of antibacterials by engineered phage

As part of the AZ Innovation Fund, the following projects were selected:

Dr David Mann & Prof Alan Armstrong:聽Targeted covalent drug discovery for Rac1

Prof Geoff Baldwin:聽Cellular delivery of PROTACS as a novel therapeutic approach

Dr Paul McKay, Dr Anna Blakney & Prof Robin Shattock:聽Optimization of Modular, Exteriorly-Loaded Lipid Nanoparticles for mRNA Delivery in Human Skin Explants

For the full list of successful proposals, and further information on the scheme, please .