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A new study has found depression is more common among people with Crohn鈥檚 disease or ulcerative colitis in the years before they are diagnosed.

Researchers from聽St George鈥檚 University of London,聽Imperial College London,聽University College London聽and聽King鈥檚 College London聽studied the records of fifteen thousand people with ulcerative colitis and Crohn鈥檚 disease, collectively known as inflammatory bowel diseases or IBD.

They found patients were more likely to be diagnosed with depression up to nine years before the diagnosis of their IBD, compared with people who did not go on to be diagnosed with IBD.

IBD can result in abdominal pain, diarrhoea or rectal bleeding and many people live with these gastrointestinal symptoms for years before being diagnosed. This study examined the link between depression and the chance of later developing IBD.

People who reported gastro-intestinal symptoms before developing depression were 40% more likely to develop IBD compared with people without depression. However, individuals with depression but no prior gastrointestinal symptoms were no more likely to be diagnosed with IBD than individuals without depression.

Depression and gut symptoms

The study suggests that, on its own, depression is not a risk factor for developing IBD, however people with depression and previous gastrointestinal symptoms may be more likely to develop either Crohn鈥檚 disease or ulcerative colitis.

Study author聽Dr Jonathan Blackwell from Imperial’s聽and聽St George’s University of London聽explained: 鈥淭he relationship between depression and IBD is unclear but it is likely some individuals develop depression as a consequence of gastrointestinal symptoms they experience before being diagnosed with IBD. If you are experiencing depression with abdominal pain, diarrhoea or rectal bleeding see your doctor and get tested because there may be a treatable cause.鈥�

, study co-author from Imperial’s聽School of Public Health, said: “The main message for GPs and clinicians is to think holistically when patients report feeling anxious or depressed in the presence of diarrhoea, abdominal pain or rectal bleeding – could all these things be related to an underlying condition such as inflammatory bowel disease?鈥�

Extra vigilance is needed during the pandemic because the usual cues for low mood anxiety or depression are hard to detect over the phone and easy to pass off as being related to the current global crisis.”

, study co-author from St George’s University of London added: 鈥淚t is possible people become depressed while living with undiagnosed gut symptoms of Crohn鈥檚 disease or ulcerative colitis. Now, more than ever, during the COVID-19 pandemic it is vital to put strategies in place to ensure timely diagnosis of these bowel conditions to protect people鈥檚 physical and mental health.鈥�

This work was funded by a grant provided by Crohn鈥檚 & Colitis UK, with infrastructure support from the 蓝莓视频 蓝莓视频.

Read the full story by Kate Wighton聽. 漏 Imperial College London

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